Community Clinic opened its doors in 1969 when a cadre of volunteer health professionals working with the City of Rockville's Roving Youth Leader Program began providing health care to teens and young adults joining the "counter culture." In 1972, CCI incorporated as a nonprofit agency and operated in a historic home in Rockville. The 1980s brought significant expansion, as CCI established clinics in Silver Spring and Gaithersburg. Now serving a rapidly growing population of uninsured and Medicaid patients, CCI added health centers in Takoma Park and Germantown in the ‘90s. In March 1996, the state of Maryland awarded CCI the Montgomery County contract for the Women, Infant and Children (WIC) nutrition education and food supplement Program, with an enrollment of 7,600 participants. Today, Community Clinic proudly serves 45,000 children and adults in Montgomery and Prince George's counties in seven permanent, well-equipped, accessible locations.

Community Clinic is a federally qualified health center (FQHC), accredited by the national Joint Commission for Accreditation of Health Care Organizations.